This is a MacOSX port of version 0.5 of Mupen64 by Adam Green and Lamer0. The demos it runs can be found at the Mac TrueReality homepage. This N64 emulator availiable for Mac runs some commercial ROMs. It can play games like Resident Evil 2, Rogue Squadron, Pokemon Snap, and World Driver Championship 'out-of-the-box' (without the need to fiddle with settings, plugins, or anything of the sort).
This is likely the most compatible N64 emulator you're going to come across. The project bundles Mupen64Plus with GLideN64, as well as its own frontend, input plugin, and netplay support. M64p is an open-source, plugin-based Nintendo 64 emulator maintained by loganmc10.
